Norepinephrine vs Epinephrine Post Cardiac Arrest

Introduction  1. The effects of epinephrine on animal hemodynamics have been studied since the late 1800s with recent concern with deleterious complications with cerebral and myocardial oxygen supply. 2. Recently, there has been consideration for norepinephrine post cardiac arrest to minimize the  complications associated with epinephrine Epinephrine  Norepinephrine Dose Weight-based dosing: • Usual dosage range: 0.01 […]

Cannabinoid Hyperemesis Syndrome (CHS)

Introduction  1. Commonly identified as symptoms, including nausea, cyclic vomiting and abdominal pain, that are refractory  to available antiemetics and analgesics.   2. Patients tend to take compulsive hot baths/showers for symptom relief.  3. Characteristically distinguished from cyclic vomiting syndrome, these symptoms are usually preceded by years  of chronic cannabis use and symptoms are typically resolved […]

Pharmacologic Management of Crotalid Envenomation

Introduction  1. Around 9,000 Americans are treated for snake bites and 5 die each year. Most are bitten by members of the Crotalinae subfamily (a.k.a.  crotalids) of the pit viper family which includes copperheads, water moccasins, and rattlesnakes.  2. Crotalid envenomation’s can cause broad range of adverse effects, including local tissue, hematologic, and/or systemic effects  […]

Oral COVID Agents

Author: Alyssa Lear, PharmD Introduction Recently, oral coronavirus agents showed treatment efficacy in clinical studies for outpatients with COVID-19 Goals of therapy for outpatients with COVID-19: Prevent serious disease, reduce visits to an urgent care/hospital, reduce duration of illness, and reduce death Fluvoxamine is FDA approved for the treatment of obsessive-compulsive disorder, but has recently […]